Chalmers Conferences, 9th European Conference on Mathematical and Theoretical Biology

Impact of treatment length and treatment default on drug-resistant tuberculosis epidemiology
Paula Rodrigues

Last modified: 2014-03-31


Tuberculosis (TB) is a leading cause of human infectious mortality. TB default is a relevant problem for this scenario reducing treatment success and increasing the risk of resistant TB. In this work we analyse the relation of treatment default to treatment length along with its consequence on the disease spreading. We find that the epidemiological benefits of shorter treatment regimens are tightly associated with increases in treatment compliance and depend on the epidemiological background. We analyse its consequences for drug-resistant tuberculosis epidemiology.


tuberculosis, treatment length, tratment default, reinfection, mathematical modeling