Chalmers Conferences, 9th European Conference on Mathematical and Theoretical Biology

On the dome formation during Zebrafish epiboly
Martin Bock

Last modified: 2014-03-28


During the sphere stage of Zebrafish development, the embryo consists of two major functional units: (1) the yolk extends in spheroidal shape from the vegetal pole, and nourishes (2) the blastoderm, flattening around the opposite animal pole. The sphere stage is an intermediate state of a larger morphogenetic process called epiboly, whereby the blastoderm extends from the animal pole and spreads over the whole surface of the yolk. In the initial phase up to 50% epiboly, the yolk simultaneously bulges out towards the blastoderm. This deformation of the yolk is called dome formation.

On my poster I explain how dome formation can be understood as a competition between surface tension and volume conservation, and how this relates to measured data from wildtype and pky-mutant embryos.


zebrafish; dome; doming; surface tension; volume conservation