Chalmers Conferences, 9th European Conference on Mathematical and Theoretical Biology

Direct evidence of the strong co-evolution of somatic and organelle genomes
Michael Sadovsky, Anna Chernyshova

Last modified: 2014-06-03


We studied a distribution of genomes of mitochondria and chloroplast genomes (separately) in 63-dimensional space yielded by the tripet frequencies of DNA. The distributions were texted against clusterization with both linear (K-means, K-line) and non-linear (rigid maps techniques) methods. Stable and clear culsterization has been observed due to both implemented techniques. Then the correspondance of the taxa composition of the observed clusters were studied. It aws found the taxa and clades occupy the clusters in extremely non-randon manner, but follow a taxonomy. This observation brings a direct and strong evidence ov the co-evolution of two genetic systems (organelle and somatic), since the proximity of genomes in frequency space was determined through a study of organelle genomes, while the taxonomy proximity was determined in standard way (i.e. independently from those genetic entities).


genome; frequency dictionary; cluster; order; structure